Symmetrel (Amantadine) – What You Need to Know

Symmetrel is the brand name for amantadine, a drug that was first used to fight the flu. Today it’s mostly prescribed for Parkinson’s disease and to treat certain movement disorders. If you’ve been told to take Symmetrel, you probably have questions about how it works, how much to take, and what to watch out for. Let’s break it down in plain language.

How Symmetrel Works and When It’s Used

Amantadine boosts dopamine activity in the brain, which helps improve motor control in Parkinson’s patients. It also has antiviral properties, but doctors rarely use it for flu nowadays because newer antivirals are better. Besides Parkinson’s, doctors may prescribe Symmetrel for drug‑induced extrapyramidal symptoms (those jerky movements you sometimes see after certain antipsychotics).

Typical Dosage and How to Take It

For Parkinson’s, the starting dose is usually 100 mg once a day. Most people end up on 200 mg per day, split into two doses (morning and evening). Your doctor will adjust based on how you feel and any side effects. Take the tablets with water; you don’t have to eat with them, but if you notice stomach upset, a small snack can help.

If you’re using Symmetrel for drug‑induced movement problems, the dose might be lower – often 50 mg twice daily. Never change the dose on your own; the amount you need can vary a lot depending on age, kidney function, and other meds you’re on.

Keep a pill organizer and set reminders so you don’t miss a dose. Skipping a dose isn’t usually dangerous, but try to stay consistent to keep symptom control steady.

Common Side Effects to Watch

Most people tolerate Symmetrel well, but some experience side effects. The most frequent are:

• Dry mouth
• Sleep disturbances (insomnia or vivid dreams)
• Dizziness or light‑headedness
• Constipation
• Swelling of the ankles

If any of these get worse or you notice new symptoms like trouble breathing, skin rash, or severe confusion, call your doctor right away. These could signal a rare but serious reaction.

Drug Interactions You Should Know

Symmetrel can interact with several other medicines. Anticholinergics (used for motion sickness) may increase side effects like dry mouth. Some antipsychotics and mood stabilizers can reduce the benefit you get from amantadine. Kidney‑affecting drugs (like certain diuretics) might require a lower Symmetrel dose.

Always give your pharmacist a full list of what you’re taking, including over‑the‑counter supplements. Vitamin C high‑dose supplements can theoretically reduce the drug’s effectiveness, though the evidence is limited.

Special Considerations

If you have kidney problems, your doctor will likely start you on a lower dose because amantadine is cleared through the kidneys. Older adults also need careful dosing and monitoring for confusion or falls.

Pregnant or breastfeeding women should discuss risks with their provider. There isn’t enough solid data to say it’s completely safe, so the decision is usually made case‑by‑case.

Tips for Safe Use

1. Stick to the prescribed schedule – consistency matters. 2. Stay hydrated; a dry mouth can be uncomfortable but drinking water helps. 3. Track any side effects in a notebook; bring it to your next appointment. 4. Avoid alcohol if you feel dizzy; it can worsen balance problems. 5. Tell every doctor you see that you’re on Symmetrel, especially if you need surgery.

Understanding how Symmetrel works and what to expect makes it easier to manage your health. If anything feels off, reach out to your healthcare team – they’re there to help you stay safe and feel better.