Amantadine: What It Is, How to Use It, and What to Watch For

Ever heard of amantadine and wondered why doctors keep mentioning it? In plain words, it’s a pill that was first made to fight the flu, but over time doctors found it helps with Parkinson’s disease and some movement problems. Let’s break down the basics so you know when it’s useful, how to take it, and what side effects might pop up.

When Do Doctors Prescribe Amantadine?

Amantadine works by increasing dopamine levels in the brain and by blocking a certain virus from spreading. Because of that, you’ll see it used for two main reasons:

• Parkinson’s disease: It can reduce stiffness, tremors, and the “off” periods when medication wears off.
• Flu prevention (rare now): Earlier, it was given after exposure to the flu virus to keep a mild case from becoming severe.

Sometimes doctors also try it for certain drug‑induced movement disorders, like the extra movements some antipsychotics cause.

How to Take Amantadine – Dosage Made Simple

Dosage depends on why you’re taking it and how your body reacts. Here’s a quick snapshot:

• Parkinson’s: Start low, usually 100 mg once a day, then climb to 100 mg twice daily. Some people need up to 200 mg three times a day.
• Flu exposure: The old regimen was 200 mg once, then 100 mg daily for a few days. Most doctors don’t use this anymore.

Always swallow the tablet with water. If you miss a dose, take it as soon as you remember – unless it’s almost time for the next one. In that case, skip the missed dose; don’t double up.

Take it with food if your stomach feels uneasy. Some folks report fewer stomach aches that way.

Side Effects You Might Feel

Like any medicine, amantadine can cause unwanted reactions. Most are mild, but knowing them helps you act fast if something seems off.

• Common: Nausea, dry mouth, trouble sleeping, dizziness, or light‑headedness.
• Neuro‑related: Restlessness, anxiety, or vivid dreams. If you notice sudden confusion, call your doctor.
• Skin: A rash or itching could mean an allergic reaction – stop the drug and seek help.

Serious but rare issues include swelling of the face or throat, shortness of breath, or a fast heartbeat. Those need immediate medical attention.

Tips for Safe Use

Here are easy habits that keep you on the safe side:

• Tell your doctor about other meds – especially anticholinergics, antihistamines, or other Parkinson’s drugs. Interactions can heighten side effects.
• Keep a medication list. A quick glance can prevent duplicate prescriptions.
• Check your blood pressure regularly if you have heart problems. Amantadine can affect heart rhythm.
• Avoid alcohol if you feel dizzy. Mixing can make you more unsteady.
• Don’t stop suddenly. Your doctor will taper you down to avoid withdrawal symptoms.

If you’re pregnant, planning a pregnancy, or breastfeeding, discuss risks with your clinician. The data isn’t crystal clear, so a professional opinion matters.

Bottom Line

Amantadine is a versatile drug that can help manage Parkinson’s symptoms and, historically, fight the flu. Start low, follow your doctor’s dosing plan, and watch for side effects. Keep open communication with your healthcare team, especially about other medicines you take. With the right approach, amantadine can be a helpful part of your treatment routine.