Tag: serotonin syndrome

Medications

6 Jan, 2026 2

Selegiline Transdermal and Serotonergic Drugs: How to Avoid Dangerous Interactions

Selegiline transdermal (EMSAM) is an antidepressant patch that carries serious risks when mixed with serotonergic drugs. Learn the exact washout periods, dangerous combinations, and how to avoid life-threatening serotonin syndrome.

Medications

15 Dec, 2025 11

Pharmacodynamic Drug Interactions: What Happens When Drugs Combine

Pharmacodynamic drug interactions occur when drugs alter each other's effects at the receptor level, not by changing concentrations. These can be dangerous-like serotonin syndrome-or beneficial, like antibiotic synergy. Understanding how drugs talk to each other is critical for safe prescribing.